Authors: Rubens Belfort Jr, MD, PhD; Eduardo Novaes MD, PhD; Gabriel Andrade MD; Andre Romano MD; Joao Dias MD, PhD

Inflammatory diseases including new viral entities have ocular lesions diagnosis given by optical coherence tomography (OCT), including OCT angiography (OCTA) and en face structural OCT technologies, which often replaces the expensive, time-consuming fluorescein and indocyanine green angiography previously established as the gold-standard imaging. Swept-source OCT (SS-OCT) is of particular importance in posterior uveitis as it penetrates deeper through the tissues, including the retinal pigment epithelium and choroid.

Examples showing granulomas anomalous vessels, microvascular abnormalities and vitreous, retinal and choroidal changes secondary to ocular inflammation will be shown. Also, suggestive characteristics of autoimmune diseases and viral etiology (herpetic and CMV) compared to toxoplasmosis, toxocariais, syphilis, cat-stracht disease and tuberculosis will be discussed.

The high-resolution imaging with depth resolved visualization of the superficial and deep retinal capillary plexus coupled to en face structural OCT, even not detecting leakage, greatly reveals important details about the location and extent of disease, progression and response to therapy and should be routinely performed.